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Articles - Vitamin B12 and the metabolic rate
Article 3
Vitamin B12 and the metabolic rate
Vitamin B12, also known as cobalamin, is naturally found
in food such as fish, milk and milk products, eggs, meat and
poultry. Fortified breakfast cereals are another source of
vitamin B12 and a valuable source for vegetarians. Vitamin
B12 is important for good health, necessary for the proper
digestion and absorption of foods and for normal metabolism
of carbohydrates, and fat. It helps maintain healthy nerve
cells and red blood cells and is needed to make DNA. Vitamin
B12 is bound to the protein in food. Hydrochloric acid in
the stomach releases B12 from protein during digestion.
Vitamin B12 was isolated from a liver extracted in 1948 and
identified as the nutritional factor in liver that prevented
pernicious anemia, a deadly type of anemia characterized by
large, immature red blood cells. In order to absorb the small
amounts of vitamin B12 found in food, the stomach secretes
intrinsic factor, a special digestive secretion that increases
the absorption of vitamin B12 in the small intestine. Unlike
other water-soluble nutrients, vitamin B12 is stored in the
liver, kidney, and other body tissues. It can take several
years before signs of the deficiency appear, all because of
poor dietary intake.
Vitamin B12 functions as a "methyl donor." A methyl
donor is a compound that carries and donates methyl groups
to other molecules, including cell membrane components and
neurotransmitters. As a methyl donor vitamin B12 is involved
in homocysteine metabolism and plays a critical role in proper
energy metabolism, immune function, and nerve function. Therefore,
vitamin B12 is clearly an added benefit for anyone wanting
to lose weight, as without it, metabolism is not at its peak
potential.
Dosing for vitamin B12 is dependent on the age of the individual
as well as if the patient is pregnant or lactating. Vitamin
B12 is necessary in only very small quantities No one has
ever reported clear toxicity from vitamin B12.
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